Follow along as we talk with partners from various European high-tech research and innovation projects. What is the impact they are making on tomorrow by the work they are doing today? From short term challenges to long-term goals, see how your tax money supports innovation throughout Europe.
Factsheet #8: FL
Security & Safety
Factsheet #8: FL
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prividema website
Scientific Publication
Security & Safety
Scientific Publication
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forres website
Factsheet #7: European Impact
Security & Safety
Factsheet #7: European Impact
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prividema website
PhotoGeNIC Factsheet 6: Applications of Germanium Photonics
Circuits & Systems
PhotoGeNIC Factsheet 6: Applications of Germanium Photonics
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photogenic website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Factsheet #6: FHE
Security & Safety
Factsheet #6: FHE
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prividema website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Factsheet #5: Use Cases
Security & Safety
Factsheet #5: Use Cases
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prividema website
Factsheet #4: CTI
Security & Safety
Factsheet #4: CTI
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prividema website
Factsheet #3: EUDI Wallet Ecosystem
Security & Safety
Factsheet #3: EUDI Wallet Ecosystem
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prividema website
Factsheet #2: Biometrics
Security & Safety
Factsheet #2: Biometrics
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prividema website
6GTandem Newsletter Issue 06
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Signals & Communication
6GTandem Newsletter Issue 06
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6gtandem website
6GTandem Newsletter Issue 06
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Industrial & Production Engineering
6GTandem Newsletter Issue 06
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addmorepower website
Scientific publication
Industrial & Production Engineering
Scientific publication
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milado website
Factsheet #1: PRIVIDEMA
Security & Safety
Factsheet #1: PRIVIDEMA
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prividema website
Paper Published: The Proceedings of the 24th European Conference on Cyber Warfare and Security, ECCWS 2025
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Security & Safety
Paper Published: The Proceedings of the 24th European Conference on Cyber Warfare and Security, ECCWS 2025
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dynamo website
Paper Published: Proceedings of the 20th International Conference on Cyber Warfare and Security, ICCWS 2025
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Security & Safety
Paper Published: Proceedings of the 20th International Conference on Cyber Warfare and Security, ICCWS 2025
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dynamo website
Journal Article submitted to “Optimization Methods and Software”
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Security & Safety
Journal Article submitted to “Optimization Methods and Software”
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prividema website
Journal Article published in “IACR Transactions on Symmetric Cryptology”
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Security & Safety
Journal Article published in “IACR Transactions on Symmetric Cryptology”
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prividema website
D11.1 – Plan for dissemination and exploitation incl. communication activities
Industrial & Production Engineering
D11.1 – Plan for dissemination and exploitation incl. communication activities
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amusens website
Explainer Video
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Aerospace & Defense
Explainer Video
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operant website
D5.3 – Dissemination report on structured illumination demonstrator results
Circuits & Systems
D5.3 – Dissemination report on structured illumination demonstrator results
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realholo website
D4.3 – Dissemination report on MR Head Up Display demonstrator
Circuits & Systems
D4.3 – Dissemination report on MR Head Up Display demonstrator
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realholo website
D3.7 – Dissemination report on MEMS results
Circuits & Systems
D3.7 – Dissemination report on MEMS results
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realholo website
Paper
Industrial & Production Engineering
Paper
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amusens website
Poster
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Industrial & Production Engineering
Poster
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amusens website
Poster
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Industrial & Production Engineering
Poster
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amusens website
Poster
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Industrial & Production Engineering
Poster
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amusens website
D6.3 – Report on user needs for the development of a single sensor
Industrial & Production Engineering
D6.3 – Report on user needs for the development of a single sensor
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amusens website
D6.2 – Algorithm for the selection of most promising materials by AI
Industrial & Production Engineering
D6.2 – Algorithm for the selection of most promising materials by AI
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amusens website
D6.1 – Database of gas sensing responses
Industrial & Production Engineering
D6.1 – Database of gas sensing responses
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amusens website
D1.1 – Project Quality Plan
Industrial & Production Engineering
D1.1 – Project Quality Plan
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amusens website
D6.12 – Professional communication kits – Version 4
Circuits & Systems
D6.12 – Professional communication kits – Version 4
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realholo website
D6.8 – Final dissemination report
Circuits & Systems
D6.8 – Final dissemination report
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realholo website
Conference Paper published: PKC 2026
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Security & Safety
Conference Paper published: PKC 2026
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prividema website
Paper published: Accurate and Composable Noise Estimates for CKKS with Application to Exact HE Computation
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Security & Safety
Paper published: Accurate and Composable Noise Estimates for CKKS with Application to Exact HE Computation
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prividema website
PhotoGeNIC Factsheet 05: Integration of Germanium Photonics on Silicon
Circuits & Systems
PhotoGeNIC Factsheet 05: Integration of Germanium Photonics on Silicon
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photogenic website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
D6.4 WP3, WP4, WP5 Demonstrator Platform
Security & Safety
D6.4 WP3, WP4, WP5 Demonstrator Platform
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orshin website
D5.3 Intra-device and inter-device secure communication prototypes
Security & Safety
D5.3 Intra-device and inter-device secure communication prototypes
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orshin website
D5.2 Report about essential and beyond-essential s&p guarantees for intra-device communication in restricted environments
Security & Safety
D5.2 Report about essential and beyond-essential s&p guarantees for intra-device communication in restricted environments
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orshin website
D5.1 Report about Essential and Beyond Essential S&P Guarantees for Inter-device Communication in Restricted Environments
Security & Safety
D5.1 Report about Essential and Beyond Essential S&P Guarantees for Inter-device Communication in Restricted Environments
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orshin website
D4.2 Prototype of automatic security pre-silicon SW testing
Security & Safety
D4.2 Prototype of automatic security pre-silicon SW testing
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orshin website
D4.1 Report on security audit and testing
Security & Safety
D4.1 Report on security audit and testing
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orshin website
D3.3 Models for formal verification
Security & Safety
D3.3 Models for formal verification
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orshin website
D3.2 Hardware implementations of cryptographic building blocks with formally verifiable protection against physical attacks
Security & Safety
D3.2 Hardware implementations of cryptographic building blocks with formally verifiable protection against physical attacks
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orshin website
D3.1 RISC-V processor with countermeasures against microarchitectural attacks
Security & Safety
D3.1 RISC-V processor with countermeasures against microarchitectural attacks
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orshin website
MILADO Newsletter Issue 03
Industrial & Production Engineering
MILADO Newsletter Issue 03
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milado website
Factsheet#4: Sub-THz systems coping with an elephant in the room: strengthen first, standardize next
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Signals & Communication
Factsheet#4: Sub-THz systems coping with an elephant in the room: strengthen first, standardize next
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6gtandem website
Factsheet#4: Sub-THz systems coping with an elephant in the room: strengthen first, standardize next
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Industrial & Production Engineering
Factsheet#4: Sub-THz systems coping with an elephant in the room: strengthen first, standardize next
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addmorepower website
Paper published: European Conference on Knowledge Management (ECKM 2025), Vol. 26(1)
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Security & Safety
Paper published: European Conference on Knowledge Management (ECKM 2025), Vol. 26(1)
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dynamo website
Paper published: European Conference on Knowledge Management (ECKM 2025), Vol. 26(1)
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Security & Safety
Paper published: European Conference on Knowledge Management (ECKM 2025), Vol. 26(1)
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dynamo website
Paper published: European Conference on Research Methodology for Business and Management Studies (ECRM 2025), Vol. 24(1)
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Security & Safety
Paper published: European Conference on Research Methodology for Business and Management Studies (ECRM 2025), Vol. 24(1)
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dynamo website
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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Security & Safety
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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dynamo website
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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Security & Safety
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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dynamo website
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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Security & Safety
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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dynamo website
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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Security & Safety
Paper published: European Conference on Cyber Warfare and Security (ECCWS 2025), Vol. 24(1)
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dynamo website
Paper published: 20th International Conference on Cyber Warfare and Security (ICCWS 2025)
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Security & Safety
Paper published: 20th International Conference on Cyber Warfare and Security (ICCWS 2025)
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dynamo website
Paper published: 2025 6th INTERNATIONAL CONFERENCE IN ELECTRONIC ENGINEERING & INFORMATION TECHNOLOGY (EEITE 2025)
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Security & Safety
Paper published: 2025 6th INTERNATIONAL CONFERENCE IN ELECTRONIC ENGINEERING & INFORMATION TECHNOLOGY (EEITE 2025)
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dynamo website
Paper published: Information & Security: An International Journal, Vol. 55(3), 2024
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Security & Safety
Paper published: Information & Security: An International Journal, Vol. 55(3), 2024
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dynamo website
Paper published: Information & Security: An International Journal, Vol. 55(3), 2024
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Security & Safety
Paper published: Information & Security: An International Journal, Vol. 55(3), 2024
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dynamo website
Paper published: Information & Security: An International Journal, Vol. 55(1), 2024
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Security & Safety
Paper published: Information & Security: An International Journal, Vol. 55(1), 2024
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dynamo website
Paper published: WSEAS Transactions on Computers, Vol. 23 (2024)
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Security & Safety
Paper published: WSEAS Transactions on Computers, Vol. 23 (2024)
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dynamo website
Paper published: Lecture Notes in Computer Science (LNCS), Security and Privacy in Smart Environments (Springer)
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Security & Safety
Paper published: Lecture Notes in Computer Science (LNCS), Security and Privacy in Smart Environments (Springer)
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dynamo website
PhotoGeNIC Newsletter Issue #3
Circuits & Systems
PhotoGeNIC Newsletter Issue #3
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photogenic website
Factsheet No 2 – Additive Manufacturing for gas sensor fabrication
Industrial & Production Engineering
Factsheet No 2 – Additive Manufacturing for gas sensor fabrication
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amusens website
ForRES Factsheet 5
Security & Safety
ForRES Factsheet 5
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forres website
Publication in Journal of Physics D: Applied Physics
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Circuits & Systems
Publication in Journal of Physics D: Applied Physics
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photogenic website
Factsheet #3: 6GTandem Use Cases
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Signals & Communication
Factsheet #3: 6GTandem Use Cases
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6gtandem website
Factsheet #3: 6GTandem Use Cases
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Industrial & Production Engineering
Factsheet #3: 6GTandem Use Cases
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addmorepower website
Third ForRES Newsletter
The third issue of the ForRES Newsletter is now available. Download to get an overview of the latest developments within the project.
Security & Safety
Third ForRES Newsletter
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forres website
Factsheet #4: QCLs
Industrial & Production Engineering
Factsheet #4: QCLs
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milado website
Factsheet #3: MIR Technology
Industrial & Production Engineering
Factsheet #3: MIR Technology
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milado website
Factsheet #2: MEMS
Industrial & Production Engineering
Factsheet #2: MEMS
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milado website
OPERANT Patch
The post OPERANT Patch appeared first on OPERANT - rOcket dePloyed deEp Reconnaissance ANd Transmission system.
Aerospace & Defense
OPERANT Patch
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operant website
OPERANT Poster
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Aerospace & Defense
OPERANT Poster
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operant website
OPERANT Roll Up
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Aerospace & Defense
OPERANT Roll Up
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operant website
Paper published at 2nd Cyber Security in CarS Workshop (CSCS’25)
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Security & Safety
Paper published at 2nd Cyber Security in CarS Workshop (CSCS’25)
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connect website
Factsheet No 1 – How technology helps individuals track air pollutant exposure
Industrial & Production Engineering
Factsheet No 1 – How technology helps individuals track air pollutant exposure
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amusens website
Scientific Publication
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
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Security & Safety
Scientific Publication
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orshin website
Scientific Publication
View and download paper
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
View and download paper
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
View and download paper
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
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Security & Safety
Scientific Publication
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orshin website
Scientific Publication
View and download paper
Security & Safety
Scientific Publication
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orshin website
Newsletter Issue 05
Security & Safety
Newsletter Issue 05
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connect website
Workshop Report
Security & Safety
Workshop Report
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connect website
MILADO Newsletter Issue 02
Industrial & Production Engineering
MILADO Newsletter Issue 02
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milado website
D6.2 “Integrated Framework (Final Release), Use Case Evaluation and Project Impact Assessment”
Security & Safety
D6.2 “Integrated Framework (Final Release), Use Case Evaluation and Project Impact Assessment”
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connect website
6GTandem Newsletter Issue 05
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Signals & Communication
6GTandem Newsletter Issue 05
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6gtandem website
6GTandem Newsletter Issue 05
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Industrial & Production Engineering
6GTandem Newsletter Issue 05
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addmorepower website
5GAA White Paper
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Security & Safety
5GAA White Paper
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connect website
Scientific Publication
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Security & Safety
Scientific Publication
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orshin website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Newsletter Issue 05
Security & Safety
Newsletter Issue 05
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orshin website
Scientific Publication
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
Security & Safety
Scientific Publication
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orshin website
AMUSENS 2nd Newsletter Issue
Industrial & Production Engineering
AMUSENS 2nd Newsletter Issue
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amusens website
Scientific Publication
Security & Safety
Scientific Publication
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orshin website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Newsletter Issue 01
Security & Safety
Newsletter Issue 01
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prividema website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
ORSHIN Factsheet No 5
Security & Safety
ORSHIN Factsheet No 5
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orshin website
Paper published at IEEE VNC 2025
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Security & Safety
Paper published at IEEE VNC 2025
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connect website
Demo presented at IEEE VNC 2025
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Security & Safety
Demo presented at IEEE VNC 2025
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connect website
Paper published at IEEE VNC 2025
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Security & Safety
Paper published at IEEE VNC 2025
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connect website
Scientific Publication
Security & Safety
Scientific Publication
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orshin website
D5.3 “MEC-enabled Orchestrator, Continous Authorization, Trust Management and DLT-based Secure Information Exchange”
Security & Safety
D5.3 “MEC-enabled Orchestrator, Continous Authorization, Trust Management and DLT-based Secure Information Exchange”
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connect website
D4.3 “Virtualization- and Edge-based Security and Trust Extensions (Final Release)”
Security & Safety
D4.3 “Virtualization- and Edge-based Security and Trust Extensions (Final Release)”
Paper published at IEEE Vehicular Networking Conference 2024
Security & Safety
Paper published at IEEE Vehicular Networking Conference 2024
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connect website
Paper published at IEEE Vehicular Networking Conference 2024
Security & Safety
Paper published at IEEE Vehicular Networking Conference 2024
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connect website
CONNECT Video Gallery
Watch videos
Security & Safety
CONNECT Video Gallery
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connect website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
Scientific Publication
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Security & Safety
Scientific Publication
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orshin website
DYNAMO 3rd Newsletter Issue
Security & Safety
DYNAMO 3rd Newsletter Issue
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dynamo website
D6.1 “Plan for dissemination and exploitation incl. communication activities”
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Signals & Communication
D6.1 “Plan for dissemination and exploitation incl. communication activities”
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6gtandem website
D6.1 “Plan for dissemination and exploitation incl. communication activities”
The post D6.1 “Plan for dissemination and exploitation incl. communication activities” appeared first on 6GTandem - A Dual-frequency Distributed MIMO Approach for Future 6G Applications.
Industrial & Production Engineering
D6.1 “Plan for dissemination and exploitation incl. communication activities”
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addmorepower website
D1.1 “Project quality plan”
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Signals & Communication
D1.1 “Project quality plan”
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6gtandem website
D1.1 “Project quality plan”
The post D1.1 “Project quality plan” appeared first on 6GTandem - A Dual-frequency Distributed MIMO Approach for Future 6G Applications.
Industrial & Production Engineering
D1.1 “Project quality plan”
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addmorepower website
DYNAMO Data Protection Notice
Security & Safety
DYNAMO Data Protection Notice
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dynamo website
DYNAMO 4th Factsheet: Ethics & Cybersecurity
Security & Safety
DYNAMO 4th Factsheet: Ethics & Cybersecurity
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dynamo website
Paper published: WSEAS Transactions on Computers
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Security & Safety
Paper published: WSEAS Transactions on Computers
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dynamo website
Paper published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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Security & Safety
Paper published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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dynamo website
Paper published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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Security & Safety
Paper published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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dynamo website
Paper Published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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Security & Safety
Paper Published: Proceedings of The 19th International Conference on Cyber Warfare and Security (ICCWS)
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dynamo website
D1.3 ‘Ethical and Legal Protocol and Compliance Assessment’
Security & Safety
D1.3 ‘Ethical and Legal Protocol and Compliance Assessment’
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dynamo website
Scientific Publication
The post Scientific Publication appeared first on 6GTandem - A Dual-frequency Distributed MIMO Approach for Future 6G Applications.
Signals & Communication
Scientific Publication
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6gtandem website
Scientific Publication
The post Scientific Publication appeared first on 6GTandem - A Dual-frequency Distributed MIMO Approach for Future 6G Applications.
Industrial & Production Engineering
Scientific Publication
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addmorepower website
Scientific Publication
View and Download Paper
View and Download Dataset
Security & Safety
Scientific Publication
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orshin website
Scientific Publication
View and Download
Security & Safety
Scientific Publication
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orshin website
D5.2 “Distributed Processing, Fast Offloading and MEC-enabled Orchestrator”
Security & Safety
D5.2 “Distributed Processing, Fast Offloading and MEC-enabled Orchestrator”
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connect website
D4.2 “Virtualization- and Edge-based Security and Trust Extensions”
Security & Safety
D4.2 “Virtualization- and Edge-based Security and Trust Extensions”
D7.2 “Dissemination, Communication, Clustering and Exploitation activities”
Security & Safety
D7.2 “Dissemination, Communication, Clustering and Exploitation activities”
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connect website
Publication in the Journal “Nature Communications”
Article entitled: “Rare disease research workflow using multilayer networks elucidates the molecular determinants of severity in Congenital Myasthenic Syndromes”
Biotechnology & Health
Publication in the Journal “Nature Communications”
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iPC website
Paper published at VehicleSec 2024
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Security & Safety
Paper published at VehicleSec 2024
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connect website
Paper published at ESCAR Europe 2023
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Security & Safety
Paper published at ESCAR Europe 2023
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connect website
Publication in the Journal „Cancer Cell“
Article entitled: “Integrative analysis of neuroblastoma by single-cell RNA sequencing indentifies the NECTIN2-TIGIT axis as a target for immunotherapy”
Biotechnology & Health
Publication in the Journal „Cancer Cell“
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iPC website
Paper published in ACM Transactions on Privacy and Security
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Security & Safety
Paper published in ACM Transactions on Privacy and Security
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connect website
Paper published at WONS2024
WONS2024-POLITO
Security & Safety
Paper published at WONS2024
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connect website
Publication in the Journal „Hepatology Communications”
Publication in the Journal „Hepatology Communications”
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iPC website
Paper published in Computer Communications
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Security & Safety
Paper published in Computer Communications
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connect website
Scientific Publication
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Security & Safety
Scientific Publication
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orshin website
Paper published: International Journal on Applied Physics and Engineering
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Security & Safety
Paper published: International Journal on Applied Physics and Engineering
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dynamo website
DYNAMO 3rd Factsheet: Resilience
Security & Safety
DYNAMO 3rd Factsheet: Resilience
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dynamo website
D4.1 “Conceptual Architecture of Customizable TEE and Attestation Models Specifications”
Security & Safety
D4.1 “Conceptual Architecture of Customizable TEE and Attestation Models Specifications”
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connect website
Scientific publication
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Signals & Communication
Scientific publication
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6gtandem website
Scientific publication
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Industrial & Production Engineering
Scientific publication
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addmorepower website
6GTandem Newsletter Issue 02
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Signals & Communication
6GTandem Newsletter Issue 02
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6gtandem website
6GTandem Newsletter Issue 02
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Industrial & Production Engineering
6GTandem Newsletter Issue 02
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addmorepower website
Publication in the Journal “2023 Life Science Alliance LLC”
Article entitled: “Proteomic-based stratification of intermediate-risk prostate cancer patients”
Biotechnology & Health
Publication in the Journal “2023 Life Science Alliance LLC”
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iPC website
Scientific Publication
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Signals & Communication
Scientific Publication
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Scientific Publication
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Industrial & Production Engineering
Scientific Publication
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D5.1 “Distributed Processing and CCAM Trust Functions Offloading & Data Space Modelling”
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D5.1 “Distributed Processing and CCAM Trust Functions Offloading & Data Space Modelling”
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connect website
D2.1 “Growth of VCSEL on Ge by MOCVD and MBE”
Circuits & Systems
D2.1 “Growth of VCSEL on Ge by MOCVD and MBE”
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photogenic website
ORSHIN Newsletter Issue 02
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ORSHIN Newsletter Issue 02
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orshin website
Conference Paper in ‘ISTFA 2023’
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Conference Paper in ‘ISTFA 2023’
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exfiles website
Paper published: WSEAS TRANSACTIONS on COMPUTERS
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Paper published: WSEAS TRANSACTIONS on COMPUTERS
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dynamo website
Publication in the Journal “Analytical Chemistry”
Article entitled: “Heat ‘n Beat: A universal high-throughput end-to-end proteomics sample processing platform in under an hour”
Biotechnology & Health
Publication in the Journal “Analytical Chemistry”
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iPC website
DYNAMO 2nd Newsletter Issue
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DYNAMO 2nd Newsletter Issue
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dynamo website
Scientific Publication
Signals & Communication
Scientific Publication
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6gtandem website
Scientific Publication
Industrial & Production Engineering
Scientific Publication
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addmorepower website
D1.2 “Project Quality and Risk Assessment Plan”
Circuits & Systems
D1.2 “Project Quality and Risk Assessment Plan”
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photogenic website
D7.3 “Updated plan and initial report on dissemination and communication activities”
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D7.3 “Updated plan and initial report on dissemination and communication activities”
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exfiles website
D7.2 “Hands-on trainings for contributors”
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D7.2 “Hands-on trainings for contributors”
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exfiles website
DYNAMO 2nd Factsheet: CTI
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DYNAMO 2nd Factsheet: CTI
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dynamo website
Paper published at ESORICS 2023
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Paper published at ESORICS 2023
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connect website
Publication in the Journal “Hepatology“
Article entitled “Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response”
Biotechnology & Health
Publication in the Journal “Hepatology“
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iPC website
Publication in the Journal „European Journal of Cancer”
Article entitled: “Adoptive cell therapy in pediatric extracranial solid tumors: current approaches and future challenges”
Biotechnology & Health
Publication in the Journal „European Journal of Cancer”
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iPC website
Paper published: 24th European Conference on Knowledge Management
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Paper published: 24th European Conference on Knowledge Management
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dynamo website
ForRES Leaflet
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ForRES Leaflet
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forres website
D2.1 “Operational Landscape, Requirements and Reference Architecture – Initial Version”
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D2.1 “Operational Landscape, Requirements and Reference Architecture – Initial Version”
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connect website
D1.2 “Project Quality Plan”
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D1.2 “Project Quality Plan”
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connect website
PhotoGeNIC Newsletter Issue #1
Circuits & Systems
PhotoGeNIC Newsletter Issue #1
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photogenic website
Newsletter Issue 01
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Newsletter Issue 01
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connect website
DYNAMO Introduction Webinar Flyer
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DYNAMO Introduction Webinar Flyer
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dynamo website
Paper published in PLOS ONE
Paper entitled: “Two opposing gene expression patterns within ATRX aberrant neutoblastoma”
Biotechnology & Health
Paper published in PLOS ONE
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iPC website
Paper published in PQCrypto 2023
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Paper published in PQCrypto 2023
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connect website
Paper published in Digital Discovery
Paper entitled: “Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes”
Biotechnology & Health
Paper published in Digital Discovery
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iPC website
Science Animated
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Science Animated
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connect website
Paper published in IEEE Transactions on Intelligent Vehicles
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Paper published in IEEE Transactions on Intelligent Vehicles
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connect website
Journal Paper in ‘ScienceDirect’
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Journal Paper in ‘ScienceDirect’
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exfiles website
D3.1 “Architectural Specification of CONNECT Trust Assessment Framework, Operation and Interaction”
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D3.1 “Architectural Specification of CONNECT Trust Assessment Framework, Operation and Interaction”
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connect website
Fact sheet
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Fact sheet
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connect website
Paper published at AsiaCCS conference 2023
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Paper published at AsiaCCS conference 2023
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connect website
DYNAMO 1st Factsheet: BCM
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DYNAMO 1st Factsheet: BCM
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dynamo website
Paper published in IEEE Internet of Things Magazine
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Paper published in IEEE Internet of Things Magazine
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connect website
Scientific Publication
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Scientific Publication
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orshin website
ForRES Announcement Letter
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ForRES Announcement Letter
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forres website
Paper published: BledCom 2023
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Paper published: BledCom 2023
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dynamo website
Paper published: BledCom 2023
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Paper published: BledCom 2023
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dynamo website
Paper published in IEEE VTC Spring 2023
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Paper published in IEEE VTC Spring 2023
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connect website
Press Release
Eyes and Ears for the Car of the Future
The Car2TERA project launched in 2019 has successfully concluded, advancing smart electronic sensor systems.
Circuits & Systems
Press Release
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car2tera website
Paper published: 22nd European Conference on Cyber Warfare and Security
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Security & Safety
Paper published: 22nd European Conference on Cyber Warfare and Security
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dynamo website
Paper published: 22nd European Conference on Cyber Warfare and Security
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Paper published: 22nd European Conference on Cyber Warfare and Security
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dynamo website
Paper published in Journal of Hepatology
Paper entitled: “Identification and experimental validation of druggable epigenetic targets in hepatoblastoma”
Biotechnology & Health
Paper published in Journal of Hepatology
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iPC website
Scientific Publication
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Scientific Publication
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orshin website
Paper published in Vehicular Communication
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Paper published in Vehicular Communication
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connect website
6GTandem Newsletter Issue 01
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Signals & Communication
6GTandem Newsletter Issue 01
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6gtandem website
6GTandem Newsletter Issue 01
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Industrial & Production Engineering
6GTandem Newsletter Issue 01
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addmorepower website
Scientific Publication
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Scientific Publication
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orshin website
Paper published in IEEE VNC 2023
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Paper published in IEEE VNC 2023
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connect website
Paper Published in Digital Discovery
Paper entitled: “Chemical representation learning for toxicity prediction”
Biotechnology & Health
Paper Published in Digital Discovery
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iPC website
D6.1 “Plan for dissemination and exploitation including communication activities”
Circuits & Systems
D6.1 “Plan for dissemination and exploitation including communication activities”
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photogenic website
Scientific Publication
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Scientific Publication
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orshin website
Paper published in Frontiers in Oncology
Paper entitled: “Quantitative proteomic studies addressing unmet clinical needs in sarcoma”
Biotechnology & Health
Paper published in Frontiers in Oncology
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iPC website
DYNAMO 1st Newsletter Issue
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DYNAMO 1st Newsletter Issue
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dynamo website
Paper published in The Computer Journal
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Paper published in The Computer Journal
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connect website
Scientific Publication
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Scientific Publication
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orshin website
Scientific Publication
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Scientific Publication
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orshin website
Paper published in IEEE Transactions on Circuits and Systems I: Regular Papers 2023
Paper entitled “Beyond 100-Gbps Polymer Microwave Fiber Communication Link at D-Band”
Circuits & Systems
Paper published in IEEE Transactions on Circuits and Systems I: Regular Papers 2023
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car2tera website
Paper published in Molecular Cancer Therapeutics
Paper entitled: “Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma”
Biotechnology & Health
Paper published in Molecular Cancer Therapeutics
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iPC website
Paper published in Briefings in Bioinformatics
Paper entitled: “FLAN: feature-wise latent additive neural models for biological applications”
Biotechnology & Health
Paper published in Briefings in Bioinformatics
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iPC website
4th Newsletter
The 4th and final newsletter of the Car2TERA H2020 project contains an reflection on the project, insights on the demonstrators, latest publications and dissemination activities.
Circuits & Systems
4th Newsletter
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car2tera website
Paper published in IEEE
Paper entitled: “Why the winner is the best”
Biotechnology & Health
Paper published in IEEE
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iPC website
D7.1 ‘Internal & external IT communication infrastructure (incl. Project website) & initial plan for the dissemination and communication of results’
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D7.1 ‘Internal & external IT communication infrastructure (incl. Project website) & initial plan for the dissemination and communication of results’
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dynamo website
ORSHIN Newsletter Issue 01
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ORSHIN Newsletter Issue 01
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orshin website
Fact sheet
Security & Safety
Fact sheet
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connect website
Paper in IFIP 2022
Paper entitled “A Wideband High-Gain Power Amplifier Operating in the D Band”
Circuits & Systems
Paper in IFIP 2022
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car2tera website
PMF 2023 – Presentation
High-speed data links based on polymer microwave fiber (PMF) for 5G evolution and 6G radio systems by Yinggang Li (Ericsson)
Circuits & Systems
PMF 2023 – Presentation
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car2tera website
Publication in the Journal “NAR Genomics and Bioinformatics”
Article entitled: „ Single-cell gene set enrichment analysis and transfer learning for functional annotation of scRNA-seq data”
Biotechnology & Health
Publication in the Journal “NAR Genomics and Bioinformatics”
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iPC website
D7.1 “Plan for Dissemination and Exploitation incl. Communication”
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D7.1 “Plan for Dissemination and Exploitation incl. Communication”
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connect website
Paper published: Proceedings of the 18th ICCWS
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Paper published: Proceedings of the 18th ICCWS
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dynamo website
Poster published at EUMW 2022
Poster entitled Design of 130-290 GHz rectangular polymer fibers for high-speed data links
Circuits & Systems
Poster published at EUMW 2022
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car2tera website
Paper published in the 26th International Conference on Artificial Intelligence and Statistics (AISTATS)
Paper entitled “Isotropic Gaussian Processes on Finite Spaces of Graphs”
Biotechnology & Health
Paper published in the 26th International Conference on Artificial Intelligence and Statistics (AISTATS)
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iPC website
Paper Published in Bioinformatics Advances
Paper entitled: “MonoNet: enhancing interpretability in neural networks via monotonic features”
Biotechnology & Health
Paper Published in Bioinformatics Advances
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iPC website
Paper published in the 39th Conference on Uncertainty in Artificial Intelligence (UAI 2023)
Paper entitled “Aligned Diffusion Schroedinger Bridges”
Biotechnology & Health
Paper published in the 39th Conference on Uncertainty in Artificial Intelligence (UAI 2023)
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iPC website
DYNAMO Elevator Pitch
Security & Safety
DYNAMO Elevator Pitch
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dynamo website
Paper published in EuCAP 2022
Paper entitled “Design of an Amplitude-Tapered Corporate-Feed Slot Array Antenna with Reduced Side-Lobe Level for Silicon Micromachining”
Circuits & Systems
Paper published in EuCAP 2022
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car2tera website
ETSI Research Conference 2023
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Signals & Communication
ETSI Research Conference 2023
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6gtandem website
ETSI Research Conference 2023
The post ETSI Research Conference 2023 appeared first on 6GTandem - A Dual-frequency Distributed MIMO Approach for Future 6G Applications.
Industrial & Production Engineering
ETSI Research Conference 2023
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addmorepower website
6GTandem Leaflet
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Signals & Communication
6GTandem Leaflet
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6gtandem website
6GTandem Leaflet
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Industrial & Production Engineering
6GTandem Leaflet
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addmorepower website
Paper published at IET Radar 2022
Paper entitled “ACCURATE RCS IMAGING OF CAR IN-CABIN OBJECTS AT SUB-THZ FREQUENCIES”.
Circuits & Systems
Paper published at IET Radar 2022
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car2tera website
Paper published at EuRAD 2022
Paper entitled “Radar Cross-Section Characterization of the Car In-Cabin Environment at Sub-THz Frequencies”.
Circuits & Systems
Paper published at EuRAD 2022
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car2tera website
Paper published at EuRAD 2021
Paper entitled “Concept analysis of a frequency-sweeping delta/ sigma beam-switching radar using machine learning”
Circuits & Systems
Paper published at EuRAD 2021
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car2tera website
Paper in ‘CARDIS 2022’
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Paper in ‘CARDIS 2022’
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exfiles website
Paper in ‘Cryptology ePrint Archive’
Security & Safety
Paper in ‘Cryptology ePrint Archive’
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exfiles website
6GTandem Announcement Letter
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Signals & Communication
6GTandem Announcement Letter
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6gtandem website
6GTandem Announcement Letter
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Industrial & Production Engineering
6GTandem Announcement Letter
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addmorepower website
Paper published in Transactions on Intelligent Vehicles
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Paper published in Transactions on Intelligent Vehicles
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connect website
DYNAMO Leaflet
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DYNAMO Leaflet
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dynamo website
PhotoGeNIC Leaflet
Circuits & Systems
PhotoGeNIC Leaflet
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photogenic website
Paper Published in Cell Reports
Paper entitled: “Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation”
Biotechnology & Health
Paper Published in Cell Reports
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iPC website
Paper in ‘IEEE Xplore’
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Paper in ‘IEEE Xplore’
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exfiles website
CONNECT Leaflet
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CONNECT Leaflet
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connect website
ORSHIN Leaflet
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ORSHIN Leaflet
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orshin website
Publication in the Journal “Medical Image Analysis (Elsevier)”
Article entitled: „SegPC-2021: A challenge & dataset on segmentation of Multiple Myeloma plasma cells from microscopic images”
Biotechnology & Health
Publication in the Journal “Medical Image Analysis (Elsevier)”
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iPC website
DYNAMO Announcement Letter
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Security & Safety
DYNAMO Announcement Letter
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dynamo website
CONNECT Announcement Letter
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CONNECT Announcement Letter
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connect website
ORSHIN Announcement Letter
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ORSHIN Announcement Letter
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orshin website
PhotoGeNIC Announcement Letter
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Circuits & Systems
PhotoGeNIC Announcement Letter
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photogenic website
Factsheet 4 – Main Achievements & ongoing work
The fourth iPC factsheet about the main achievements and ongoing work is now available. Much has already been done in the first two project periods to achieve the goal to improve the care of children with cancer and our partners are continuously working in the third project period to solve the mathematical and computational bottlenecks of data- and model-based medicine. Therefore, the fourth iPC factsheet describes the most important achievements so far and the ongoing work in the current project period.
Biotechnology & Health
Factsheet 4 – Main Achievements & ongoing work
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iPC website
D7.3 Identification of cell subpopulations in each tumour type, their association with response to therapy, and prediction of effective alternative therapies
Tumour decomposition into cells and subtypes and inference about the effects of treatments and perturbations on each tumour component (cell or tumor subclone).
Biotechnology & Health
D7.3 Identification of cell subpopulations in each tumour type, their association with response to therapy, and prediction of effective alternative therapies
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iPC website
Publication in the Journal “Bioinformatics”
Article entitled: “Computational modelling in health and disease: highlights of the 6th annual SysMod meeting”
Biotechnology & Health
Publication in the Journal “Bioinformatics”
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iPC website
Paper Published in Proteomics
Paper entitled: “Opportunities for pharmacoproteomics in biomarker discovery”
Biotechnology & Health
Paper Published in Proteomics
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iPC website
Factsheet 3 – iPC Open Source Software
The third iPC factsheet about the iPC Open source software is now available. It describes 3 of the 25 open source softwares that were developed during the project framework. The focus will be on INtERAcT, CONSIFER and DECODE, which were developed by our partner IBM.
Biotechnology & Health
Factsheet 3 – iPC Open Source Software
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iPC website
Paper Published in Cancers
Paper entitled: “Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma”
Biotechnology & Health
Paper Published in Cancers
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iPC website
Paper published in Proteomics
Paper entitled: “Clinical applications of mass spectrometry-based proteomics in cancer: Where are we?”
Biotechnology & Health
Paper published in Proteomics
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iPC website
Paper published
Paper entitled: “Computational challenges of cell cycle analysis using single cell transcriptomics”
Biotechnology & Health
Paper published
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iPC website
Factsheet 2 – iPC Platforms
The second iPC factsheet about the iPC Platforms is now available. It describes the 5 cloud-based platforms that were developed during the project framework from our partners BSC, XLAB, CHOP, AMC, PMC, DKFZ, UGent and BCM.
Biotechnology & Health
Factsheet 2 – iPC Platforms
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iPC website
D1.4 Model development data including genetic perturbation screens and gene-drug synergies
This deliverable reports on the generation of CROPseq and drug screening data for two Ewing Sarcoma cell lines, one Hepatoblastoma cell line and one B-cell Acute Lymphoblastic Leukemia cell line.
Biotechnology & Health
D1.4 Model development data including genetic perturbation screens and gene-drug synergies
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iPC website
Conference Paper “ECML PKDD International Workshop on eXplainable Knowledge Discovery in Data Mining”
Paper entitled: “Is Attention Interpretation? A Quantitative Assessment On Sets”
Biotechnology & Health
Conference Paper “ECML PKDD International Workshop on eXplainable Knowledge Discovery in Data Mining”
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iPC website
Paper published in Cancer Cell
Paper entitled: “Pan-cancer proteomic map of 949 human cell lines”
Biotechnology & Health
Paper published in Cancer Cell
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iPC website
Publication in the Journal “Nature Communications”
Article entitled: “The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors”
Biotechnology & Health
Publication in the Journal “Nature Communications”
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iPC website
Factsheet 1 – Tumour Type Working Groups
The first iPC factsheet on Tumour Type Working Groups is now available. It describes the 5 different types of childhood cancer and the work our partners are doing. The working groups are led by our partners IGTP, DKFZ, PMC, CURIE, UZH and MPG.
Biotechnology & Health
Factsheet 1 – Tumour Type Working Groups
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iPC website
Paper published in Nature Communication
Paper entitled: “MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma”
Biotechnology & Health
Paper published in Nature Communication
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iPC website
Paper published in Bioinformatics
Paper entitled: “DECODE: a computational pipeline to discover T cell receptor binding rules”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in Cell Reports
Paper entitled: “MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines”
Biotechnology & Health
Paper published in Cell Reports
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iPC website
D7.2 Software to define tumour subclones and association with therapy response
Flow cytometry is an important diagnostic tool in childhood acute lymphoblastic leukaemia (ALL), flow cytometry data analysis is limited by multiple sources of bias and variation. We present a unified machine learning framework for automated analysis of a standardized diagnostic paediatric leukaemia staining that can overcome these challenges. We applied our framework in a large cohort of ALL flow cytometry samples and demonstrated how it can robustly extract the frequencies of cell lineage populations with minimal expert intervention. This work provides a proof of concept that our method meets the needs of an automated analysis tool for diagnostic flow cytometry data.
Biotechnology & Health
D7.2 Software to define tumour subclones and association with therapy response
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iPC website
D8.3 Metabolic models
Oncogene-driven metabolic rewiring in cancer is key to allow proliferation of tumour cells in low nutrient and oxygen conditions. To study such phenomena, reconstructing context-specific metabolic models through omics data integration is crucial. Here we report the original pipeline to construct context-specific metabolic models from scRNA-seq data and we applied it to scRNA-seq data from Ewing Sarcoma.
Biotechnology & Health
D8.3 Metabolic models
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iPC website
D4.3 Topological analysis of multi-omics and multi-cancer molecular networks resulting in the definition of molecular mechanisms
Three types of network-based analysis of gene-gene interaction networks have been suggested and tested on the multi-omics paediatric cancer datasets. User-friendly computational environment for joint application of matrix factorization and network analysis has been implemented.
Biotechnology & Health
D4.3 Topological analysis of multi-omics and multi-cancer molecular networks resulting in the definition of molecular mechanisms
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iPC website
D8.2 Network models for molecular target identification
We focused on the development of patient specific signalling networks using prior knowledge about the molecular events and CRISPR perturbation datasets and associated the activity of the nodes of signalling network with drug response data to find molecular targets.
Biotechnology & Health
D8.2 Network models for molecular target identification
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iPC website
D4.4 Consensus multi-omics subtypes of paediatric cancers
We report on the implementation of a method for multilayer community trajectory analysis and its applications, including a published study on medulloblastoma, a study on congenital myasthenic syndromes, and a study on the functional characterization of commonalities among a selection of paediatric tumours.
Biotechnology & Health
D4.4 Consensus multi-omics subtypes of paediatric cancers
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iPC website
Consensus multi-omics subtypes of paediatric cancers
We report on the implementation of a method for multilayer community trajectory analysis and its applications, including a published study on medulloblastoma, a study on congenital myasthenic syndromes, and a study on the functional characterization of commonalities among a selection of paediatric tumours.
Biotechnology & Health
Consensus multi-omics subtypes of paediatric cancers
We report on the selection of the appropriate data models to handle the available data and metadata to the iPC Central Computational and Data platform. We also report on the current status of the development for the iPC Data portal.
Paper entitled: “Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive hepatocellular neoplasms in children and adolescents”
Biotechnology & Health
Paper published in Journal of Hepatology
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iPC website
Paper published in Molecular Cell
Paper entitled: “Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions”
Biotechnology & Health
Paper published in Molecular Cell
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iPC website
Paper published in Bioinformatics
Paper entitled: “BIODICA: a computational environment for Independent Component Analysis of omics data”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in Cancer Science
Paper entitled: “Mutational spectrum of ATRX aberrations in neuroblastoma and associated patient and tumor characteristics”
Biotechnology & Health
Paper published in Cancer Science
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iPC website
Paper published in Nature Communication
Paper entitled: “A single-cell analysis of breast cancer cell lines to study tumour heterogeneity and drug response”
Biotechnology & Health
Paper published in Nature Communication
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iPC website
Paper in ‘arXiv’
Security & Safety
Paper in ‘arXiv’
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exfiles website
Paper in ‘IEEE Security and Privacy Workshops (SPW)’
Security & Safety
Paper in ‘IEEE Security and Privacy Workshops (SPW)’
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exfiles website
Paper in ‘Computers & Security’
Security & Safety
Paper in ‘Computers & Security’
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exfiles website
Paper published in frontiers in Molecular Bioscience
Paper entitled: „Modeling Progression of Single Cell Populations Through the Cell Cycle as a Sequence of Switches“
Biotechnology & Health
Paper published in frontiers in Molecular Bioscience
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iPC website
Paper published in iScience
Paper entitled: “Machine learning for multi-omics data integration in cancer“
Biotechnology & Health
Paper published in iScience
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iPC website
D3.3 Integration of INtERAcT, MelanomaMine and LimTox and application to biomedical publications on paediatric cancers
This deliverable reports on the integration of INtERAcT and the implemented text mining workflow. The workflow was developed to adapt LimTox and MelanomaMine to pediatric tumor abstracts from PubMed and relies on INtERAcT in its downstream component of inferring molecular associations between entities extracted from unstructured text.
Biotechnology & Health
D3.3 Integration of INtERAcT, MelanomaMine and LimTox and application to biomedical publications on paediatric cancers
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iPC website
D1.3 Synthetic data for testing and training patient, cancer, and drug models
Synthetic data generation is emerging as an important solution for precision medicine. Therefore, an explainable Variational AutoEncoder (VAE) model is developed for synthetic transcriptomics data generation in medulloblastoma. The model can be used to complement and interpolate available data with synthetic instances. It is also transparent as it is able to match the learned latent variables with unique gene expression patterns. The model can also be adapted to other pediatric cancers and the resulting synthetic datasets used to test and train patient, cancer, and drug models in other work packages of the iPC project.
Biotechnology & Health
D1.3 Synthetic data for testing and training patient, cancer, and drug models
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iPC website
Paper published in BMC Bioinformatics
Paper entitled: “Emulating complex simulations by machine learning methods (SP)”
Biotechnology & Health
Paper published in BMC Bioinformatics
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iPC website
Paper will be presented at SPIE Medical Imaging
Paper entitled: “Segmentation of Multiple Myeloma Plasma Cells in Microscopy Images with Noisy Labels” (Presentation)
Biotechnology & Health
Paper will be presented at SPIE Medical Imaging
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iPC website
Paper published in bioRxiv
Paper entitled: “Loss of p16INK4a in neuroblastoma cells induces shift to an immature state with mesenchymal characteristics and increases sensitivity to EGFR inhibitors”
Biotechnology & Health
Paper published in bioRxiv
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iPC website
Paper published in BMC Bioinformatics
Paper entitled “DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification”
Biotechnology & Health
Paper published in BMC Bioinformatics
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iPC website
Paper published in Bioinformatics
Paper entitled: “FUNKI: Interactive functional footprint-based analysis of omics data”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in the Frontiers in Immunology
Paper entitled: “From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling (SP)“
Biotechnology & Health
Paper published in the Frontiers in Immunology
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iPC website
Paper published in PNAS
Paper entitled: “Defects in 8-oko-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma”
Biotechnology & Health
Paper published in PNAS
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iPC website
Paper published in Symmetry 2021
Paper entitled: “The Multiple Dimensions of Networks in Cancer: A Perspective”
Biotechnology & Health
Paper published in Symmetry 2021
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iPC website
Paper published in the Elsevier Journal
Paper entitled “Applications of single-cell and bulk RNA sequencing in onco-immunology”.
Biotechnology & Health
Paper published in the Elsevier Journal
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iPC website
Paper published in Advanced Science
Paper entitled: “CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming”
Biotechnology & Health
Paper published in Advanced Science
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iPC website
Paper published in the Special Issue Hepatoblastoma and Other Pediatric Liver Tumors
Paper entitled “Bridging molecular basis, prognosis, and treatment of pediatric liver tumors”.
Biotechnology & Health
Paper published in the Special Issue Hepatoblastoma and Other Pediatric Liver Tumors
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iPC website
Paper published in the Current Protocols in Bioinformatics.
Paper entitled “PIONEER: Pipeline for Generating High‐Quality Spectral Libraries for DIA‐MS Data”.
Biotechnology & Health
Paper published in the Current Protocols in Bioinformatics.
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iPC website
Paper published in the Journal for ImmunoTherapy of Cancer
Paper entitled “Identification and validation of viral antigens sharing sequence and structural homology with tumor-associated antigens (TAAs).”
Biotechnology & Health
Paper published in the Journal for ImmunoTherapy of Cancer
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iPC website
Paper presented in the “Computer Vision for Microscopy Image Analysis (CVMI)” workshop
Paper entitled “Unsupervised Detection of Cancerous Regions in Histology Imagery using Image-to-Image Translation”
Biotechnology & Health
Paper presented in the “Computer Vision for Microscopy Image Analysis (CVMI)” workshop
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iPC website
Paper published in Bioinformatics
Paper entitled: “Improved identification and quantification of peptides in mass spectrometry data via chemical and random additive noise elimination (CRANE)”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in Physics of Life Reviews: pp. 132-134
Paper entiteld: „Adaptation through the lense of single-cell multi-omics data Comment on “Dynamic and thermodynamic models of adaptation” by A.N. Gorban et al.”
Biotechnology & Health
Paper published in Physics of Life Reviews: pp. 132-134
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iPC website
Paper published in the BIORXIV
Paper entitled “Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults”.
Biotechnology & Health
Paper published in the BIORXIV
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iPC website
Paper published in Bioinformatics
Paper entitled: “On the feasibility of deep learning applications using raw mass spectrometry data”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in Bioinformatics
Paper entitled: “TITAN: T-cell receptor specificity prediction with bimodal attention networks“
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in NATURE COMMUNICATIONS
Paper entitled: “Restoration of the molecular clock is tumor suppressive in neuroblastoma”
Biotechnology & Health
Paper published in NATURE COMMUNICATIONS
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iPC website
Paper published in Bioinformatics
Paper entitled: “SysMod: the ISCB community for data-driven computational modelling and multi-scale analysis of biological systems”
Biotechnology & Health
Paper published in Bioinformatics
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iPC website
Paper published in the Proceedings of International Conference on Machine Learning (ICML) 2021
A new network inference algorithm from TUDA with iPC acknowledge was published in the ICML 2021. Paper entitled “Active Learning of Continuous-Time Bayesian Networks Through Interventions”.
Biotechnology & Health
Paper published in the Proceedings of International Conference on Machine Learning (ICML) 2021
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iPC website
Publication in the Journal “Briefings in Bioinformatics”
Publication in the Journal “Briefings in Bioinformatics”
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iPC website
Paper published in Nature Biotechnology
Paper entitled: “The RNA Atlas expands the catalog of human non-coding RNAs”
Biotechnology & Health
Paper published in Nature Biotechnology
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iPC website
D4.2 An interactive online atlas of interconnected network maps based on the NaviCell platform
With the development of the NaviCell 3.0 web server, there is a complete and automated web-based infrastructure for hosting molecular maps, patient similarity network maps, and multi-omics datasets for the project. The NaviCell platform supports molecular map navigation and exploration using the Google maps engine. The logic of navigation is taken from Google maps. This NaviCell 3.0 web-server is freely available and several step-by-step tutorials are accessible.
Biotechnology & Health
D4.2 An interactive online atlas of interconnected network maps based on the NaviCell platform
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iPC website
D7.1 Application of software enabling computational deconvolution of bulk RNA-sequencing data to immune cell profiles of patient samples
Computational deconvolution of bulk RNA-sequencing data to infer cell type composition of a sample is challenging. Benchmarking of various computational deconvolution tools revealed various data processing parameters that impact deconvolution accuracy and revealed the importance of a complete reference matrix. As a complete reference matrix is often not available, an algorithm was designed that can handle missing cell types. This algorithm can be applied to establish the immune cell repertoire of primary tumor biopsies without prior knowledge of the full spectrum of cell types in the biopsy.
Biotechnology & Health
D7.1 Application of software enabling computational deconvolution of bulk RNA-sequencing data to immune cell profiles of patient samples
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iPC website
D3.1 Identification of important regulatory elements using multi-level matrix factorization approaches
D3.1 describes the techniques for dimensionality reduction used in iPC and their application to a selection of cohorts (at different omics levels) as well as a meta-analysis of the four solid tumor types of interest. The goal of the deliverable is to provide a list of pathways and biological functions having a key role in multiple paediatric cancers.
Biotechnology & Health
D3.1 Identification of important regulatory elements using multi-level matrix factorization approaches
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iPC website
D3.2 Adaptation of MelanomaMine and LiMTox to the analysis of paediatric cancers and application to biomedical publications on paediatric cancers
The paper reports on the implementation of the iPC text mining workflow and three use cases for extracting biomedical information from large volumes. The workflow builds on the general framework of two text mining tools, LimTox and MelanomaMine. These tools will be used in the framework of the iPC project but also beyond, having a clear impact in the research community.
Biotechnology & Health
D3.2 Adaptation of MelanomaMine and LiMTox to the analysis of paediatric cancers and application to biomedical publications on paediatric cancers
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iPC website
D8.1 Data-driven model for molecular targets and drug repositioning
This deliverable provides a detailed overview of the proposed computational tool for predicting patient-specific drugs with potential therapeutic benefit for paediatric cancer treatment and provides, for example, evidence for the goodness of the model in predicting such patient-specific drugs.
Biotechnology & Health
D8.1 Data-driven model for molecular targets and drug repositioning
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iPC website
D2.3 Recommended metadata standards and portal prototype
The iPC project aims to ensure interoperability of data between different resources, so the platform must enforce principles and well-defined standards for data accessibility, usability, and registration. This deliverable provides an overview of the different approaches to representing metadata within the iPC Platform, and the efforts to integrate and leverage them within the iPC Catalog and the overall iPC Central Computational and Data Platform to enable meaningful management of research data.
Biotechnology & Health
D2.3 Recommended metadata standards and portal prototype
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iPC website
D1.2 Collection of high-quality clinical and molecular paediatric cancer datasets as well as other tumour types
In this deliverable, demographic, clinical, and molecular profiles were collected for several pediatric and adult tumors. In addition, the focus here is on collections of single cell profiles of high risk cancers. The datasets will be used to evaluate the effects of treatments and perturbations on cancer cells, build models, and provide information on deciphering regulatory interactions. These data will allow characterization of cancer cell types that predict treatment outcome, as well as cell types that are resistant to therapies.
Biotechnology & Health
D1.2 Collection of high-quality clinical and molecular paediatric cancer datasets as well as other tumour types
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iPC website
“Estimage: a webserver hub for the computation of methylation age (SP)”
Article published in the Nucleic Acids Research Journal.
Biotechnology & Health
“Estimage: a webserver hub for the computation of methylation age (SP)”
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iPC website
“Artificial Intelligence in Cancer Research: learning at different levels of data granularity”
Article published in the Molecular Oncology Journal, Volume 15, Issue 4 Pages 817-829.
Biotechnology & Health
“Artificial Intelligence in Cancer Research: learning at different levels of data granularity”
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iPC website
Article published in the Cancer Cell Journal, Volume 39, Issue 6, P 810-826
Article entitled “STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma”.
Biotechnology & Health
Article published in the Cancer Cell Journal, Volume 39, Issue 6, P 810-826
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iPC website
“The multilayer community structure of medulloblastoma”
Article published in the iScience Journal, Volume 24, ISSUE 4 by partner Barcelona Supercomputing Center (BSC).
Biotechnology & Health
“The multilayer community structure of medulloblastoma”
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iPC website
Paper published in Machine Learning: Science and Technology
Paper entitled: “Data-driven molecular design for discovery and synthesis of novel ligands: a case study on SARS-CoV-2”
Biotechnology & Health
Paper published in Machine Learning: Science and Technology
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iPC website
Publication in the Journal of Medical Internet Research (JMIR).
Article entitled “Artificial Intelligence–Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development”.
Published in the JMIR, Volume 23 Issue 3 by partner Barcelona Supercomputing Center (BSC).
Biotechnology & Health
Publication in the Journal of Medical Internet Research (JMIR).
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iPC website
“Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell”
Article published in the Science Advances Journal, Vol. 7, no. 6.
Biotechnology & Health
“Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell”
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iPC website
Paper published in Scientifc Reports
Paper entitled: “MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma”
Biotechnology & Health
Paper published in Scientifc Reports
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iPC website
Paper published in the International Joint Conference on Neural Networks-2021 (IJCNN2021)
Paper entitled: “Clinical trajectories estimated from bulk tumoral molecular proles using elastic principal trees”
Biotechnology & Health
Paper published in the International Joint Conference on Neural Networks-2021 (IJCNN2021)
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iPC website
D4.1 Building of cancer type-specific multi-layered molecular and patient similarity networks
iPC uses network inference techniques and applies a selection of pediatric patient cohorts at different omic levels. Networks will be generated, for example, for the generation of molecular patient networks to be used in downstream project activities involving the use of networks.
Biotechnology & Health
D4.1 Building of cancer type-specific multi-layered molecular and patient similarity networks
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iPC website
“Benchmarking of cell type deconvolution pipelines for transcriptomics data”
Article published in “Nature Communications” (2020, 11:5650) by partner UGENT
Biotechnology & Health
“Benchmarking of cell type deconvolution pipelines for transcriptomics data”
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iPC website
“FPGA Accelerated Analysis of Boolean Gene Regulatory Networks”
Article published in the IEEE/ACM Transactions on Computational Biology and Bioinformatics ( Volume: 17, Issue: 6)
Biotechnology & Health
“FPGA Accelerated Analysis of Boolean Gene Regulatory Networks”
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iPC website
“COSIFER: a Python package for the consensus inference of molecular interaction networks”
Article published in the Bioinformatics Journal.
Biotechnology & Health
“COSIFER: a Python package for the consensus inference of molecular interaction networks”
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iPC website
Paper published in Briefings in Bioinformatics
Paper entitled: “Deep learning in systems medicine”
Biotechnology & Health
Paper published in Briefings in Bioinformatics
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iPC website
D2.2 “Initial infrastructure framework”
An initial demonstrator of the iPC infrastructure is reviewed. The platform’s architecture is based on modules, which allow parallel developments and integration of different open source-based software components. This allows us to leverage other efforts and contribute towards its sustainability and maintainability. The release of a minimum viable platform is allowing us to capture early feedback from researchers at iPC.
Biotechnology & Health
D2.2 “Initial infrastructure framework”
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iPC website
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